Thursday, 11 January 2018

Causes Of Kawasaki Disease + Its Health Complications

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Kawasaki disease causes inflammation in the walls of medium-sized arteries throughout the body. It primarily affects children. The inflammation tends to affect the coronary arteries, which supply blood to the heart muscle. Kawasaki disease is sometimes called mucocutaneous lymph node syndrome because it also affects lymph nodes, skin, and the mucous membranes inside the mouth, nose and throat. The cause of Kawasaki disease isn't fully understood, but the condition is thought to be caused by an infection. Genetics may also increase the chance of developing the condition.

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Complications
Doctors can manage the symptoms of Kawasaki disease if it's caught early. Most kids will feel better within 2 days of starting treatment. Heart problems usually won't develop if Kawasaki disease is treated within 10 days of the start of symptoms. Untreated cases can lead to more serious complications, such as vasculitis , an inflammation of the blood vessels. This can be particularly dangerous because it can affect the coronary arteries, which supply blood to the heart. Besides the coronary arteries, the heart muscle, lining, valves, and the outer membrane around the heart can become inflamed. Arrhythmias (changes in the normal pattern of the heartbeat) or abnormal functioning of some heart valves also can occur.

Causes
The cause of Kawasaki disease is unknown. It does not appear to be hereditary or contagious. Because the illness frequently occurs in outbreaks, an infectious agent (such as a virus) is the likely cause. Sometimes more than one child in a family can develop Kawasaki disease, which may indicate a genetic predisposition for the disease. The causes of Kawasaki Disease includes :

Genetics
The children who develop Kawasaki disease may be genetically predisposed to it. This means the genes they inherit from their parents may make them more likely to get the condition. One theory is that rather than there being a single gene responsible for Kawasaki disease, it may be the result of many genes that each slightly increase the chances of a child developing the condition. Kawasaki disease is more common in children from northeast Asia, especially Japan and Korea. This also suggests there may be a genetic cause.

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Infection
The symptoms of Kawasaki disease are similar to those of an infection, so bacteria or a virus may be responsible. However, so far a bacterial or viral cause hasn't been identified. As Kawasaki disease isn't contagious, it can't be passed from one person to another. This makes it unlikely that it's caused by a virus alone.
Kawasaki disease doesn't usually affect babies under six months old, although sometimes very young children can develop the condition. This suggests that newborn babies are protected by antibodies passed on to them by their mother, either before birth or during breastfeeding. Antibodies are proteins that destroy disease-carrying organisms. As few older children and adults are affected by Kawasaki disease, they may be immune to whatever causes it. While many people are exposed to Kawasaki disease, only a few go on to develop the symptoms.

Kawasaki Disease is a disease that causes inflammation in your body, mainly the blood vessels and lymph nodes. It mainly affects children under the age of 5, but anyone can contract Kawasaki Disease. The symptoms are similar to a fever, but they show up in two distinct stages. A persistent, high fever that lasts for more than five days, a strawberry tongue, and swollen hands and feet are a few of the symptoms of the early stage. In the later stage, symptoms may include joint paint, skin peeling, and abdominal pain.
Talk to your doctor if your child shows any of these symptoms. In some children, the symptoms may appear incomplete, but KD can cause serious heart problems, if left untreated. About 25 percent of the cases that do develop into heart disease are due to misdiagnosis and delayed treatment.


There’s no specific diagnostic test for KD. Your doctor will look at your children’s symptoms and preform tests to rule out other conditions. Timely treatment can significantly improve the outcome for children with KD.



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Author: Richard Smith