Thursday, 18 January 2018

Alarming Causes Of Dry Eye Syndrome And Treatments

Alarming Causes Of Dry Eye Syndrome And Treatments



Dry eye syndrome (DES) also called dry eye, dry eye disease, or keratoconjunctivitis sicca (KCS) is a common condition of the tear film that affects a significant percentage of the population, especially those older than 40 years of age. Dry eye syndrome can affect any race and is more common in women than in men. Another term used for dry eye is ocular surface disease. See your doctor right away if you have dry eyes and a sudden increase in discomfort or a sudden decrease in your ability to see.

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Reading extensively, working on the computer, or spending long hours in a dry environment may further aggravate your eyes if you have this condition. If you have dry eye syndrome, your eyes may also be prone to bacterial infections or the surface of your eyes may become inflamed, causing scarring on your cornea. Although it’s uncomfortable, dry eye syndrome almost never causes permanent vision loss.

Causes Of Dry Eye Syndrome

An adequate and consistent layer of tears on the surface of the eye is essential to keep your eyes healthy, comfortable and seeing well. Tears bathe the eye's surface to keep it moist and wash away dust, debris and microorganisms that could damage the cornea and lead to an eye infection.
Factors that can contribute to dry eye includes :

  • Medications including antihistamines, decongestants, antidepressants, birth control pills, hormone replacement therapy to relieve symptoms of menopause, and medications for anxiety, Parkinson’s disease, and high blood pressure have been associated with dry eye.
  •  Autoimmune disorders such as Sjögren’s syndrome, lupus, scleroderma, and rheumatoid arthritis and other disorders such as diabetes, thyroid disorders, and Vitamin A deficiency are associated with dry eye. 
  • Advancing age is a risk factor for declines in tear production. Dry eye is more common in people age 50 years or older.
  •  Windy, smoky, or dry environments increase tear evaporation. 
  • Women are more likely to develop dry eye. Hormonal changes during pregnancy and after menopause have been linked with dry eye. Women also have an increased risk for autoimmune disorders.

Diseases associated with dry eyes include vitamin A deficiency, autoimmune/connective tissue disease, hepatitis C infection, HIV infection, Sjögren's syndrome, sarcoidosis, diabetes mellitus , and androgen  or estrogen deficiency.



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Wearing contact lenses increases the risk of dry eye syndrome. Refractive surgery, especially LASIK , frequently causes dry eyes.

Diagnosis
Schirmer’s test may also be used to measure how quickly your eyes produce tears. This tests your rate of tear production using a paper wick placed on the edge of your eyelid. Different dyes may be used during a patient's eye examination. These are placed into the tears in the form of a drop. Fluorescein is a yellow dye that stains the cornea where epithelial (surface) cells have been worn away because of the lack of an adequate protective tear film. Rose Bengal is a red dye that stains the cornea and the conjunctiva where the cells are dead or dying as well as where healthy cells are inadequately protected by the tear film. Lissamine Green is a green dye which can help differentiate between normal and abnormal surface cells of the cornea and conjunctiva.

Treatments For Dry Eye Syndrome

  • Testosterone cream : It doesn’t happen often, but dry eye can be related to a lack of testosterone in the oil glands on your eyelids. The doctor might give you a testosterone cream that you apply to your eyelids. It can help your oil glands work better.
  •  Over-the-counter (OTC) topical medications : Mild dry eye symptoms may be treated with over-the-counter medications such as artificial tears, gels, and ointments.
  • Lacrimal Plugs : Your eye doctor might use plugs to block the drainage holes in the corners of your eyes. This is a relatively painless, reversible procedure that slows tear loss. If your condition is severe, the plugs may be recommended as a permanent solution. 
  • Surgery : Punctal plugs made of silicone or collagen may be inserted by an eye care professional to partially or completely plug the tear ducts at the inner corners of the eye to keep tears from draining from the eye. In severe cases, surgical closure of the drainage ducts by thermal punctal cautery may be recommended to close the tear ducts permanently.
  • Good nutrition : You need a well-balanced diet with enough protein and vitamins to keep your eyes healthy. Omega-3 essential fatty acid supplements are sometimes recommended to enhance the oil content of the eye. Usually, people need to take these supplements regularly for at least three months to see an improvement. 
  • Environmental and lifestyle changes. Cutting back on screen time and taking periodic eye breaks may help. Closing the eyes for a few minutes, or blinking repeatedly for a few seconds, may replenish basal tears and spread them more evenly across the eye. Sunglasses that wrap around the face and have side shields that block wind and dry air can reduce symptoms in windy or dry conditions. In cases of Meibomian gland dysfunction, warm lid compresses and scrubs may be helpful. Smoking cessation and limiting exposure to secondhand smoke also may help.
  •  Antibiotics : Antibiotic ophthalmic ointments, such as erythromycin and bacitracin, among others, are used at night for about 7-10 days to decrease the number of bacteria that break down the lipid layer of the tear film. These ointments also lubricate the eyes overnight. Oral antibiotics, particularly tetracycline and doxycycline , not only help to decrease the number of bacteria, but also help to make the oil more fluid so it flows out of the oil glands more easily.

If the eyes are dry mainly while reading or watching TV, taking frequent breaks to allow the eyes to rest and become moist and comfortable again is helpful. Closing the eyes for 10 seconds every five to 10 minutes will increase comfort, as will blinking more frequently.



7 Causes,Treatment And Warnings Of Eye Pain - Stop Eye Pain

7 Causes,Treatment And Warnings Of Eye Pain - Stop Eye Pain

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Eye pain is often described as burning, sharp, shooting, dull, gritty, a feeling of "something in my eye," aching, pressure, throbbing, or stabbing. Sometimes pain originating from the eye is confused with other symptoms, such as a headache , sinus pain, toothache , or a migraine . Eye pain is a common reason for people to seek medical care from their doctor (or an ophthalmologist, a medical doctor specializing in the diagnosis and treatment of eye diseases).

Symptoms Of Eye Pain
With eye pain, there may be other symptoms too, which may help diagnose the cause of the discomfort. These include:

  • Conjunctivitis - red itchy eyes
  • Tears
  • Light sensitivity (photophobia)
  • Discharge, which can be clear, or thick and coloured (pus)
  • The eye being crusted shut after sleep due to discharge
  • Foreign body sensation - the feeling that something is in the eye, whether or not anything actually is
  • Nausea or vomiting
  • Decreased vision
  • Headache

Causes Of Eye Pain


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  • Corneal abrasions and corneal ulcerations are also common conditions that cause eye pain. The cornea is the transparent surface of the eye. Abrasions occur from scratches to the surface of the cornea, such as from trauma , a foreign body in the eye or overuse of contact lenses . Ulcerations occur from infections or abrasions. Foreign bodies, usually located on the cornea or in the conjunctiva, are objects or materials that give the sensation that something is in eye. Foreign bodies produce eye pain similar to that of corneal abrasions.
  • Chemical burns and flash burns are significant causes of eye pain. Chemical burns come from eye exposure to acid or alkaline substances, such as household cleaners or bleach. Flash burns occur from intense light sources, such as arc welding or the ultraviolet rays of tanning booths, when improper eye protection is worn. Even an intense sunny day can cause a corneal flash burn
  • Sinusitis, which is a bacterial or viral infection of the sinuses, can cause a sensation of orbital or eye socket pain. Pain coming from the sinus cavities can be interpreted as eye pain.
  • Acute angle closure glaucoma can cause orbital pain, although most cases of glaucoma are of the open-angle variety and are painless. Glaucoma is caused by an increase in intraocular pressure , or internal eye pressure, which can ultimately lead to defects in vision and even blindness if left untreated. Intraocular pressure can increase because of a blockage of outflow or increased production of aqueous humor (the fluid that bathes the inner eye). This is typically seen in older adults. 
  • Traumatic events, such as a penetrating injury to the eye, a blow to the eye with a foreign object, and motor-vehicle collisions, are causes of significant eye pain and injury. Scratches to the cornea typically associated with traumatic events are very painful. These are common eye problems that lead people to seek medical attention.
  • Migraines are a very common cause of orbital eye pain associated with headaches .
  • Tooth pain resulting from problems with the upper teeth may present as pain in the orbit or below the eye.
  • Conjunctivitis is one of the most common eye problems, Conjunctivitis can be an allergic, bacterial, chemical, or viral inflammation of the conjunctiva (the delicate membrane lining the eyelid and covering the eyeball). Pinkeye is a nonmedical term usually referring to a viral conjunctivitis, because the conjunctiva gets inflamed and turns a pinkish color. Pain is usually mild with conjunctivitis, or there is no pain at all. Itching, redness, and drainage are typical symptoms and signs associated with conjunctivitis.

Any Treatments?

It’s really important to see your eye specialist or doctor if you encounter eye pain, especially if the pain does not subside. While it’s unlikely your sore eyes will be a symptom of a very serious condition, it’s still a possibility, and you should get an expert diagnosis. Treatments obviously depend on the cause, and can be as simple as using eye drops or compresses for dry eyes and allergies, to medication and surgery for more serious eye conditions.

If you experience sudden eye pain combined with blurred vision, haloes around lights, nausea or vomiting, it could be symptom of acute closed-angle glaucoma. This is a medical emergency, and you should seek medical attention straight away.



Wednesday, 17 January 2018

About Huntington's Disease, Its Causes, Effects And Effective Treatments

About Huntington's Disease, Its Causes, Effects And Effective Treatments

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Huntington's disease is an inherited disease that causes the progressive breakdown (degeneration) of nerve cells in the brain. Huntington's disease has a broad impact on a person's functional abilities and usually results in movement, thinking (cognitive) and psychiatric disorders. Huntington disease is a progressive brain disorder that causes uncontrolled movements, emotional problems, and loss of thinking ability (cognition). Adult-onset Huntington disease, the most common form of this disorder, usually appears in a person's thirties or forties. Early signs and symptoms can include irritability, depression, small involuntary movements, poor coordination, and trouble learning new information or making decisions.
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Many people with Huntington disease develop involuntary jerking or twitching movements known as chorea. As the disease progresses, these movements become more pronounced. Affected individuals may have trouble walking, speaking, and swallowing.

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Symptoms Of Huntington Disease

According to the Huntington's Disease Society of America (HDSA), the symptoms of HD can feel like having amyotrophic lateral sclerosis (ALS), Parkinson's and Alzheimer's all in one, the symptoms include:

  • Personality changes, mood swings, and depression 
  • Problems with memory and judgment
  • Unsteady walk and uncontrollable movements
  • Difficulty speaking and swallowing, and weight loss.
  • Small changes in coordination and clumsiness
  • Stumbling 
  • Slight signs of mood and emotional change
  • Lack of focus, slight concentration problems, and difficulty functioning, for example, at work
  • Lapses in short-term memory
  • Depression 
  • Irritability

Causes Of Huntington's Disease
Huntington's disease is caused by an inherited defect in a single gene. Huntington's disease is an autosomal dominant disorder, which means that a person needs only one copy of the defective gene to develop the disorder.
With the exception of genes on the sex chromosomes, a person inherits two copies of every gene one copy from each parent. A parent with a defective gene could pass along the defective copy of the gene or the healthy copy. Each child in the family, therefore, has a 50 percent chance of inheriting the gene that causes the genetic disorder.
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Treatment For Huntington Disease
Huntington disease is currently incurable. There is no treatment that can reverse its progression or slow it down.

  1. Diagnosis : The doctor will examine the patient and ask about family and medical history, and symptoms, such as recent emotional changes. If they suspect Huntington disease, they will refer the patient to a neurologist.
  2. Speech therapy : Speech therapy can help patients find ways to express words and phrases and communicate in a more effective way.
  3. Physical and occupational therapy : A physical therapist can help improve muscle strength and flexibility, leading to better balance and a reduced the risk of falling.
  4. An occupational therapist can help the patient develop strategies for coping with concentration and memory problems, as well as making the home safer.
  5. Medications : Tetrabenazine (Xenazine) is approved by the Food and Drug Administration (FDA) to treat the jerky, involuntary movements, or chorea, associated with HD.

Regardless, some regions of the world offer medical cannabis to those diagnosed with Huntington’s disease. This enables people with the conditions to take matters into their own hands and administer cannabis if they are experiencing results from the herb.
Although cannabis remains an illegal substance at the federal level in the United States, numerous states have made the herb legal and available to medical patients.




Know Celiac Disease Causes, Foods To Avoid, Symptoms And Dangers

Know Celiac Disease Causes, Foods To Avoid, Symptoms And Dangers


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Celiac disease is an immune disease in which people can't eat gluten because it will damage their small intestine. If you have celiac disease and eat foods with gluten, your immune system responds by damaging the small intestine. Gluten is a protein found in wheat, rye, and barley. It may also be in other products like vitamins and supplements, hair and skin products, toothpastes, and lip balm. There are more than 300 symptoms of celiac disease, and symptoms can be different from person to person. Your doctor may diagnose celiac disease with a medical and family history, a physical exam, blood tests, an intestinal biopsy, a skin biopsy, and genetic tests.

If you have symptoms of celiac disease, especially ones that last a long time, you should ask your doctor for a celiac disease blood test. Celiac disease affects each person differently. Symptoms may occur in the digestive system, or in other parts of the body. One person might have diarrhea and abdominal pain, while another person may be irritable or depressed. Irritability is one of the most common symptoms in children. Some people have no symptoms.


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Causes Of Celiac Disease
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When the body's immune system overreacts to gluten in food, the reaction damages the tiny, hair-like projections (villi) that line the small intestine. Villi absorb vitamins, minerals and other nutrients from the food you eat. If your villi are damaged, you can't get enough nutrients, no matter how much you eat. Celiac disease occurs from an interaction between genes, eating foods with gluten and other environmental factors, but the precise cause isn't known.

Infant feeding practices, gastrointestinal infections and gut bacteria might contribute to developing celiac disease.Sometimes celiac disease is triggered or becomes active for the first time after surgery, pregnancy, childbirth, viral infection or severe emotional stress.

Foods To Avoid
Avoid unless the label says gluten-free:
. beer . bread . cakes and pies
. candy . cereals . cookies
crackers . croutons . gravies
. imitation meats or seafood
. oats . pasta . processed lunch meats, sausages, and hot dogs
. salad dressings
sauces (includes soy sauce)
. self-basting poultry . soups

Dangers Of Celiac Disease

1. Lactose intolerance. Damage to your small intestine may cause you to experience abdominal pain and diarrhea after eating lactose-containing dairy products, even though they don't contain gluten.
2. People with celiac disease who don't maintain a gluten-free diet have a greater risk of developing several forms of cancer, including intestinal lymphoma and small bowel cancer.
3. Malabsorption of calcium and vitamin D can contribute to reproductive issues like infertility and miscarriages.
4. Loss of calcium and bone density (osteomalacia or rickets)
5. The damage to your small intestine means it can't absorb enough nutrients.
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5 Quick Foods That Can Cause Hair Loss, Take Note Of Them

5 Quick Foods That Can Cause Hair Loss, Take Note Of Them

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Some foods are best to avoid or minimize if you’re trying to naturally re-grow your hair and reverse baldness. In some cases
certain food groups could be
triggering hair loss, and reducing the amount of them in your diet can have a significant impact on your hairline. In most cases, thanks to beauty of science, hair loss is a treatable condition and we’re continually learning ways to keep it at bay.

 When it comes to nutrition, moderation is the key and while there is no one food that can prevent hair loss, there are foods that you can avoid which would ordinarily rob the body of vital nutrients needed for healthy hair growth.

Foods That Can Cause Hair Loss

1. Carbonated drinks
Carbonated drinks are hugely acid forming. In fact they are the most acid forming food or beverage of them all. Not only this, but the sheer about of sugar in them causes blood sugar levels to spike and then crash. Dr Mercola has researched the link between excess blood sugar and male pattern baldness and has this to say about it.
“There is strong evidence that early male-pattern baldness could be a clinical marker of insulin resistance , a condition in which you lose your sensitivity to insulin, resulting in excess blood sugar.”
This provides us with another general rule that is: eat foods with low glycemic indices, so as not to spike blood sugar levels . Find out about the glycemic index of many foods and more about Dr. Mercolas research in our hair loss course.


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2. Fried Food
Consumption of high fat, fried foods and hydrogenated oils should be avoided at all costs. Studies have linked monounsaturated and saturated fat to increased testosterone levels which could potentially lead to elevated levels of DHT (a by-product that causes hair loss) while hydrogenated oils are thought to affect
hair growth by suppressing essential fatty acids needed for healthy hair. Not just that, high-fat diets can lead to diabetes, coronary disease, and obesity.

3. Food Additives
The growing demand for natural and organic foods isn’t without good cause. Hair loss can be triggered by certain food additives such as caramel colour, which may be processed with caustic chemicals, sulphites or ammonia. Even natural additives have been associated with hair loss. Cochineal extract or carmine dye – a colour additive extracted from dried bugs and commonly used in fruit drinks, sweets, yoghurt and other foods is thought to cause hair loss along with a number of life-threatening allergic reactions.

4. High-mercury Fish
Dermatologists warn that diets with large amounts of certain kinds of fish may lead to hair loss. Eating fish that is high in mercury can raise mercury levels and cause hair to thin and fall out. Ahi and Bigeye tuna, king mackerel, tilefish, swordfish, marlin and shark are all high in mercury and should be avoided.

5. Alcohol
The specific link between excess alcohol and hair loss is still unknown, studies point to heavy drinking as a possible factor in hair loss. The University of Maryland Medical Center suggests that avoiding stimulants, including alcohol and tobacco may help reduce symptoms of hair loss. Some specialists suggest that excess alcohol can inhibit hair’s ability to absorb zinc and other minerals essential for healthy hair and can cause hair loss. Others believe that heavy drinking promotes dehydration , which in turn contributes hair.



Sure Treatments Methods And Diagnosis For Sarcoidosis

Sure Treatments Methods And Diagnosis For Sarcoidosis



Sarcoidosis is an inflammatory disease in which granulomas, or clumps of inflammatory cells, form in various organs. This causes organ inflammation. Sarcoidosis may be triggered by your body’s immune system responding to foreign substances, such as viruses, bacteria, or chemicals. Sarcoidosis was once considered a rare disease. We now know that it is a common chronic illness that appears all over the world. Indeed, it is the most common of the scarring lung disorders and occurs often enough in the United States for Congress to have declared a national Sarcoidosis Awareness Day in 1990. Anyone can get sarcoidosis. It occurs in all races and in both sexes. Nevertheless, the risk is greater if you are a young black adult, especially a black woman, or of Scandinavian, German, Irish, or Puerto Rican origin. No one knows why.
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Because sarcoidosis can escape diagnosis or be mistaken for several other diseases, we can only guess at how many people are affected. The best estimate today is that about five in 100,000 white people in the United States have sarcoidosis. Among black people, it occurs more frequently, in probably 40 out of 100,000 people. Overall, there appear to be 20 cases per 100,000 in cities on the East Coast and somewhat fewer in rural locations. Some scientists, however, believe that these figures greatly underestimate the percentage of the U.S. population with sarcoidosis.


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Sarcoidosis mainly affects people between 20-40 years of age. White women are just as likely as white men to get sarcoidosis, but the black female gets sarcoidosis two times as often as the black male. No one knows what causes sarcoidosis.

Diagnosis For Sarcoidosis
Sarcoidosis can be difficult to diagnose because the disease produces few signs and symptoms in its early stages. When symptoms do occur, they may mimic those of other disorders. Your doctor may ask you detailed questions about your medical history, the methods of diagnosis includes :

Physical Exam
Your doctor will check you for signs and symptoms of sarcoidosis. Signs and symptoms may include red bumps on your skin; swollen lymph nodes; an enlarged liver, spleen, or salivary glands; or redness in your eyes. Your doctor also will check for other causes of your symptoms.
Your doctor may listen to your lungs and heart. Abnormal breathing or heartbeat sounds could be a sign that sarcoidosis is affecting your lungs or heart.

Diagnostic Tests
You may have tests to confirm a diagnosis and to find out how sarcoidosis is affecting you. Tests include a chest x ray , lung function tests , biopsy, and other tests to assess organ damage.

Chest X Ray
A chest x ray is a painless test that creates pictures of the structures inside your chest, such as your heart and lungs. The test may show granulomas or enlarged lymph nodes in your chest. About 95 percent of people who have sarcoidosis have abnormal chest x rays.

Lung Function Tests
Lung function tests measure how much air you can breathe in and out, how fast you can breathe air out, and how well your lungs deliver oxygen to your blood. These tests can show whether sarcoidosis is affecting your lungs.

Biopsy
Your doctor may do a biopsy to confirm a diagnosis or rule out other causes of your symptoms. A biopsy involves taking a small sample of tissue from one of your affected organs. Usually, doctors try to biopsy the organs that are easiest to access. Examples include the skin, tear glands, or the lymph nodes that are just under the skin.
If this isn't possible, your doctor may use a positron emission tomography (PET) scan to pinpoint areas for biopsy. For this test, a small amount of radioactive substance is injected into a vein, usually in your arm.
The substance, which releases energy, travels through the blood and collects in organs or tissues. Special cameras detect the energy and convert it into three-dimensional (3D) pictures.
If lung function tests or a chest x ray shows signs of sarcoidosis in your lungs, your doctor may do a bronchoscopy (bron-KOS-ko-pee) to get a small sample of lung tissue.


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Kveim test
This test involves injecting a standardized preparation of sarcoid tissue material into the skin. On the one hand, a unique lump formed at the point of injection is considered positive for sarcoidosis. On the other hand, the test result is not always positive even if the patient has sarcoidosis.
The Kveim test is not used often in the United States because no test material has been approved for sale by the U.S. Food and Drug Administration. However, a few hospitals and clinics may have some standardized test preparation prepared privately for their own use.

Gallium scanning
In this procedure, the doctor injects the radioactive chemical element gallium-67 into the patient's vein. The gallium collects at places in the body affected by sarcoidosis and other inflammatory conditions. Two days after the injection, the body is scanned for radioactivity. Increases in gallium uptake at any site in the body indicate that inflammatory activity has developed at the site and give an idea of which tissue, and how much tissue, has been affected. However, since any type of inflammation causes gallium uptake, a positive gallium scan does not necessarily mean that the patient has sarcoidosis.

Blood test
Blood analyses can evaluate the number and types of blood cells in the body and how well the cells are functioning. They can also measure the levels of various blood proteins known to be involved in immunological activities, and they can show increases in serum calcium levels and abnormal liver function that often accompany sarcoidosis.
Blood tests can measure a blood substance called angiotensin converting enzyme (ACE). Because the cells that make up granulomas secrete large amounts of ACE, the enzyme levels are often high in patients with sarcoidosis. ACE levels, however, are not always high in sarcoidosis patients, and increased ACE levels can also occur in other illnesses.

Treatments For Sarcoidosis
There's no cure for sarcoidosis, but in half of cases it goes away on its own. You may not even need treatment if you don't have significant signs and symptoms of the condition, but you should be monitored with regular chest X-rays and exams of the eyes, skin and any other organ involved.
Treatments generally fall into two categories -- maintenance of good health practices and drug treatment. Good health practices include:

  • Getting regular check-ups with your health care provider
  • Eating a well- balanced diet with a variety of fresh fruits and vegetables
  • Drinking enough fluids every day
  • Getting six to eight hours of sleep each night
  • Exercising regularly and managing your weight
  • Quitting smoking

Drug treatments are used to relieve symptoms and reduce the inflammation of the affected tissues. The oral corticosteroid prednisone is the most commonly used treatment. Fatigue and persistent cough are usually improved with steroid treatment. If steroids are prescribed, you should see your doctor at regular intervals so that he or she can monitor the disease and the side effects of treatment. Other treatment options include methotrexate( Otrexup,
Rheumatrex), hydroxychloroquine ( Plaquenil ), and other drugs.




Alarming Things That Causes Of Sarcoidosis, Note This!

Alarming Things That Causes Of Sarcoidosis, Note This!



Sarcoidosis is a disease that results from a specific type of inflammation of tissues of the body. It can appear in almost any body organ, but it starts most often in the lungs or lymph nodes. Lofgren's syndrome, a type of sarcoidosis, is more common in people of European descent. Lofgren's syndrome may involve fever, enlarged lymph nodes, arthritis (usually in the ankles), and/or erythema nodosum. Erythema nodosum is a rash of red or reddish-purple bumps on your ankles and shins. The rash may be warm and tender to the touch.


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Sarcoidosis is somewhat more common in women than in men. The disease usually develops between the ages of 20 and 50. People who have a family history of sarcoidosis also are at higher risk for the disease. Researchers have looked for a link between sarcoidosis and exposure to workplace and environmental factors. However, no clear link has been found. Sarcoidosis can affect any organ in your body. However, it's more likely to affect some organs than others. The disease usually starts in the lungs, skin, and/or lymph nodes (especially the lymph nodes in your chest). Also, the disease often affects the eyes and liver. Although less common, sarcoidosis can affect the heart and brain, leading to serious complications.
If many granulomas form in an organ, they can affect how the organ works. This can cause signs and symptoms. Signs and symptoms vary depending on which organs are affected. Many people who have sarcoidosis have no signs or symptoms or mild ones.

Risk factors
While anyone can develop sarcoidosis, factors that may increase your risk include:

  • Age and sex : Sarcoidosis often occurs between the ages of 20 and 40. Women are slightly more likely to develop the disease. 
  • Race : African-Americans have a higher incidence of sarcoidosis than do white . 
  • Americans : Also, sarcoidosis may be more severe and may be more likely to recur and cause lung problems in African-Americans. 
  • Family history : If someone in your family has had sarcoidosis, you're more likely to develop the disease.


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Complications  
For most people, sarcoidosis resolves on its own with no lasting consequences. But sometimes it causes long-term problems.
  • Lungs : Untreated pulmonary sarcoidosis can lead to permanent scarring in your lungs, making it difficult to breathe.
  • Eyes : Inflammation can affect almost any part of your eye and can eventually cause blindness. Rarely, sarcoidosis also can cause cataracts and glaucoma.
  • Kidneys : Sarcoidosis can affect how your body handles calcium, which can lead to kidney failure. 
  • Heart : Granulomas in your heart can cause abnormal heart rhythms and other heart problems. In rare instances, this may lead to death. 
  • Nervous system : A small number of people with sarcoidosis develop problems related to the central nervous system when granulomas form in the brain and spinal cord. Inflammation in the facial nerves, for example, can cause facial paralysis.

Causes Of Sarcoidosis
The cause of sarcoidosis isn't known. More than one factor may play a role in causing the disease. Some researchers think that sarcoidosis develops if your immune system responds to a trigger, such as bacteria, viruses, dust, or chemicals. Normally, your immune system defends your body against foreign or harmful substances. For example, it sends special cells to protect organs that are in danger.
These cells release chemicals that recruit other cells to isolate and destroy the harmful substance. Inflammation occurs during this process. Once the harmful substance is gone, the cells and the inflammation go away.
In people who have sarcoidosis, the inflammation doesn't go away. Instead, some of the immune system cells cluster to form lumps called granulomas in various organs in your body.